Can Dupixent Cause Weight Gain Hair Loss Diarrhea Or Headache
Dupixent should not cause weight gain, hair loss, diarrhea, or headache. These problems werent reported as side effects during studies of the drug.
Keep in mind that other drugs may be used along with Dupixent. These drugs, such as corticosteroids, often cause multiple side effects.
If you have concerns about any side effects while youre using Dupixent, talk with your doctor.
Who Is At Risk For Developing Dyshidrotic Eczema
There are a variety of factors that may dictate who develops dyshidrotic eczema.
If you are going to develop it, itll most likely begin between 20 and 40 years of age. Genetics may also play a role in dyshidrotic eczema. If you have one or more blood relatives with it, theres a higher chance you could also have it.
A few other factors that may contribute to its development are:
- youre already living with another type of eczema
- youve worked, or currently work, as a mechanic or metalworker
- you have a history of working with cement
- you already deal with seasonal allergies
- youre living with asthma
- you have occasional bouts of allergic sinusitis
How Long Does It Last
In many cases, pompholyx will clear up on its own within a few weeks. The treatments below may help relieve your symptoms in the meantime.
Sometimes pompholyx may just occur once and never come back, but it often comes and goes over several months or years. Any of the triggers mentioned above can cause it to flare up again.
Occasionally, pompholyx can be more continuous and difficult to treat.
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Treatment And Medication Options For Dyshidrotic Eczema
While there is no cure for dyshidrotic eczema, as Lio says, you can manage most of the symptoms on your own with a doctors direction.
Typically, we start with gentle skin care and avoiding triggers, he says. I have some favorite gentle cleansers to use instead of harsh soaps, some super-protective moisturizers, and even a gentle hand sanitizer. If that is enough , then we can get by without any medications at all.
Dr. Kindred says that keeping skin moisturized is an important part of treating dyshidrotic eczema. Use lotions containing ceramides and then cover with a barrier ointment, such as petroleum jelly, she says.
The AAD has additional tips for self-care, such as how to cleanse, moisturize, and avoid triggers.
But with more severe dyshidrotic eczema, medication and other treatments are necessary for symptom relief, say both doctors.
Questions About Dupixents Dosage
Below are some common questions about Dupixents dosage.
- What if I miss a dose of Dupixent? If you miss your dose of Dupixent, inject the dose within 7 days of missing it. But if you miss your dose by more than 7 days, skip the missed dose. Then, wait until its time to take your next scheduled dose of Dupixent.
- Will I need to use Dupixent long term? Dupixent is meant to be used long term. If you and your doctor decide that Dupixent is safe and effective for you, youll likely take it long term.
- How long does Dupixent take to work? Dupixent begins to work in your body after the first injection. But it may be a few weeks to months before you notice symptom relief.
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What Can People With Ad Do To Prevent Or Treat Eczema On Their Feet
Irritation from sweat, from socks, and friction is a major cause for foot eczema in people with AD. A moist environment can also predispose feet to infections.
Choose comfortable shoes that are not too tight and are made from materials that allow air flow. Take your shoes off as much as possible. If they have laces, dont tie them tightly, and untie them when you are not walking.
Socks lined with roughly woven or seamed fabric can be hard on your skin. If you need to wear thick socks for protection under athletic shoes or work boots, wear a thin, smooth sock or sock liner under them. Liners made of polypropylene, Merino wool, silk, or nylon work well. An absorbent outer sock can help wick sweat away from your feet.
If your feet sweat enough to keep your socks damp even when youre not exercising or doing manual work, you may benefit from a treatment to reduce sweating. Some options are prescription strength antiperspirant, tap water iontophoresis , oral glycopyrrolate pills, and Botox injections. Ask your doctor about the risks and costs of each of these treatments in order to choose the best one for you.
Avoid using topical steroids more than twice a day or for more than a few days in a row. While these medications are soothing, frequent and prolonged use can weaken the skin and make it more susceptible to damage, creating a vicious cycle of worsening when the medication is stopped. Protopic and Elidel dont cause this problem and can be used for longer periods of time.
What Are The Complications Of Vesicular Hand/foot Dermatitis
Secondary bacterialinfection with Staphylococcus aureus and/or Streptococcus pyogenes is common in vesicular hand/foot dermatitis and results in pain, swelling, and pustules on the hands and/or feet.
When involving the distal finger adjacent or proximal to the nail fold, it can result in paronychia and nail dystrophy with irregular pitting and ridges.
Infected vesicular hand dermatitis
- Soothing emollient lotions and creams
- Potent antiperspirants applied to palms and soles at night
- Protective gloves should be worn for wet or dirty work
- Well-fitting footwear, with 2 pairs of socks to absorb sweat and reduce friction.
Contact with irritants such as water, detergents, and solvents must be avoided as much as possible and protective gloves worn to prevent irritant contact dermatitis.
- Note that cream cleansers are not antimicrobial soap and water or a sanitiser is needed for washing hands in order to destroy pathogens such as the SARS-CoV-2 virus responsible for COVID-19.
People with vesicular hand dermatitis found to be allergic to nickel must try to avoid touching nickel items.
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What Is Dishydrotic Eczema
Dyshidrotic eczema, also known as pompholyx, is a type of eczema characterized by the presence of vesicles or bullae on the hands and feet. This is usually chronic persistent or recurrent. These vesicles or bullae are not boils . Dyshidrotic eczema is not an infectious condition although it may occur in a person with a fungal or bacterial infection of the hand or feet. The rash is intensely itchy with vigorous scratching leading to rupture of blisters with cracking of the skin and fissures.
It may appear an an independent entity or occur with atopic dermatitis or contact dermatitis . It may also be associated with a number of systemic, non-dermatological diseases like HIV infection. Dyshidrotic eczema may occur either on the hands or the feet or both the palms and soles are more often affected, often with extensive involvement of the fingers when it occurs on the hand.
Milder cases may resolve before vesicles rupture and therefore cracking is avoided. These cases are more likely to be noticed on the hands. Due to the psychosocial impact of this type of skin disease on the hands, many patients will seek medical attention as soon as possible. However, it may be just as common on the feet although not noticed or even reported in the early stages.
Diagnosis Of Dyshidrotic Eczema
Diagnosis of dyshidrotic eczema is as follows:
- Typically a clinical diagnosis
- Bacterial culture and sensitivity can rule out secondary infection
- Patch testing to exclude allergic contact dermatitis
- Recalcitrant cases warrant systemic evaluation
- KOH wet mount to exclude dermatophyte infection
- Punch biopsy for direct immunofluorescence to exclude bullous pemphigoid
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Treatments Your Physician May Prescribe
To manage dyshidrotic eczema, your physician may recommend soaks with drying agents if many blisters are present, as well as the removal of any potential irritating agents.
- Medium- and high-potency topical steroids may be prescribed to be used twice daily. Use of a high-potency topical steroid initially that is tapered to an as-needed basis may be most beneficial.
- An oral steroid can very effective and fast in controlling symptoms, but treatment with oral steroids is often less desirable, as tapering off the medication can result in severe flares of the disease.
- Chronic, severe disease can be treated with a form of ultraviolet light therapy called PUVA or narrow-band UVB phototherapy administered by a dermatologist.
Mental Health And Dyshidrotic Eczema
In addition to physical anguish, flare-ups of dyshidrotic eczema can lead to mental anguish. For those whose hands are affected, it is in a highly visible area that can’t be covered with clothing, so many patients feel ashamed or embarrassed about their skin, notes Lio. Also, severe cases can interfere with a person’s ability to work or carry out routine daily tasks involving hands or feet stressful situations brought on by a condition that itself is aggravated by stress.
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Will My Itp Treatment Change Over Time Will I Be On Treatment For The Rest Of My Life
Since adult ITP is generally a chronic disease, people living with the condition will often cycle through many different types of treatment throughout their lifetime.
Dr. Ivy Altomare is an associate professor of medicine at Duke University Medical Center. She has clinical expertise in a wide variety of hematological and oncological conditions and diagnoses and has been conducting clinical and health services research in the field of ITP for over a decade. She is the honored recipient of both the Junior Faculty and Senior Faculty Teaching awards at Duke University and has a special interest in medical education for both patients and physicians.
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What Does Dyshidrotic Eczema Look Like
Dyshidrotic eczema, or pompholyx,is a type of skin rash that is characterized by small to large fluid-filled blisters known as vesicles or bullae respectively. It is an itchy skin condition that often arises in the presence of other skin or systemic diseases. Scratching excessively and rupturing of the blisters leads to cracking of the skin and the formation of fissures that can be painful. This carries the additional risk of a secondary bacterial infection leading to oozing and further inflammation of the skin.
Dyshidrotic dermatitis arises on the palms of the hands and soles of the feet. In the early stages, the blisters on the feet may go by unnoticed and patients often find the rash on the hands more distressing. The blisters may also extend to the sides of the fingers and toes without underlying inflammation and redness of the skin . With an infection, pustules with a yellowish discharge may develop alongside the clear fluid-filled vesicles or bullae. Various deformities of the fingernails may be seen in more severe or long standing cases as is described under fingernail ridges, thickened fingernails and discolored nails. Changes in the nails may also be related to a fungal infection with overlapping dyshidrotic eczema.
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Signs And Symptoms Of Dyshidrotic Eczema
Signs and symptoms of dyshidrotic eczema are as follows:
- Symmetrical crops of clear vesicles and/or bullae
- Intensely purpuric
- Typically present on the palms and soles, as well as the lateral aspects of fingers and toes
- Deep-seated vesicles with a tapiocalike appearance
- May become large, form bullae, and become confluent
- In chronic disease, fingernails may reveal dystrophic changes
- Vesicles typically resolve without rupturing, followed by desquamation
What Are The Treatments For Severe Hand Eczema
If your hand eczema is severe, discuss the possibility of a dermatology referral with your GP. The referral may be for diagnosing contact allergy or for treatment, which may include a short course of oral steroids or immunosuppressants . Alternatively, dermatology departments may recommend alitretinoin or phototherapy, as described below.
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How Often Will I Have To Go To The Doctor For Testing How Important Is Ongoing Testing
An ongoing relationship with an experienced hematologist is critical for anyone with ITP. The frequency of testing will vary depending on if youre actively bleeding or your platelets are extremely low.
Once a new treatment is started, testing may be done daily or weekly. If platelets are in a safe range because of remission or due to active treatment , testing can be done monthly or every few months.
one report ). Its more common to achieve durable remission after effective treatment.
Some treatments are given for a defined duration in hopes of achieving a prolonged treatment-free period, each with varying response rates. This includes steroids, IVIG, mAbs, and splenectomy. Other treatments are continuously administered to maintain platelets in a safe range. This includes TPO-RAs, SYK inhibitors, and chronic immunosuppressants.
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What Is Dyshidrotic Eczema Symptoms Causes Diagnosis Treatment And Prevention
Dyshidrotic eczema is a type of dermatitis that affects the hands and feet. It is also known as dyshidrosis, dyshidrotic dermatitis, foot-and-hand eczema, pompholyx, and vesicular eczema, according to the American Academy of Dermatology Association .
It is characterized by tiny blisters or vesicles, usually between the digits, and it can be extremely itchy, says Peter Lio, MD, a dermatologist who is a clinical assistant professor in the department of dermatology and pediatrics at Northwestern Universityâs Feinberg School of Medicine in Chicago, as well as a board member and scientific advisory committee member for the National Eczema Association . Certain triggers can also make it flare, such as contact with irritating chemicals like soaps or detergents or hand sanitizers, sweating, seasonal changes, and sometimes even just stress.
Other causes and triggers include allergic skin reactions, atopic dermatitis, fungal and bacterial infections, exposure to nickel or cobalt, and excessive exposure to water, according to Chesahna Kindred, MD, a dermatologist in Columbia, Maryland, who is an assistant professor at Howard University College of Medicine in Washington, DC.
Dyshidrotic eczema is also a side effect of intravenous immunoglobulin infusions , which are typically used to treat certain immune system diseases, according to the AAD. Exposure to cement is another risk factor.
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Is There A Difference Between Eczema And Dermatitis
Although the terms dermatitis and eczema may overlap in how theyre used, specific types of skin conditions are better known by just one of the names. For example, many doctors use the terms atopic dermatitis and eczema interchangeably but wouldnt use the term contact dermatitis in place of eczema.
There are also a number of distinct types of eczema and dermatitis, and, to complicate matters, its possible to have more than one type at the same time.
While both eczema and dermatitis typically cause redness and itching, some types also cause blistering and peeling.
Treatments For Mild Outbreaks
Pimecrolimus cream, tacrolimus ointment, or Eucrisa, are typically used to treat atopic dermatitis. But they have also been shown to be effective for dyshidrotic eczema.
For mild flare-ups, your doctor may recommend:
- a moisturizer thats very emollient to help relieve the dryness
- a prescription corticosteroid that helps heal the blisters and reduces inflammation
- anti-itch medication in the form of a pill or cream
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Hand Eczema Dos And Don’ts For Cleansing
We do not have a cure, but we have many good treatments and many more in development. Usually we can help people get their skin much better so that they can be comfortable and return to normal activities, says Lio.
Some people have a single outbreak that clears without treatment, but it is much more common to have recurring flare-ups throughout life, according to the AAD.
Favorite Online Support Networks For Dyshidrotic Eczema
This blog is for families who are managing allergies, asthma, and eczema in their household, with a focus on natural remedies and periodic contributions by medical professionals and other guest bloggers. Check with your doctor before trying any new remedies or products, but consider this site a resource for what your peers may be exploring and finding success with. They also have a private with more than 2,800 members.
The NEA hosts this message-board-driven online forum for sharing support and advice about living with eczema. A keyword search for members posts about hand eczema brings up 927 posts going back over several years. Registration is free.
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Dyshidrotic Eczema Can Affect Your Quality Of Life
When you have blisters on your feet, wearing shoes can feel painful. Some people who get blisters on their feet say its too painful to walk until the blisters clear.
Flare-ups that lead to blisters on the hands can cause other problems. During flare-ups, the pain can limit what you can do with your hands. An auto mechanic or florist may be unable to perform certain jobs.
Some people are more likely than others to develop dyshidrotic eczema. To find out if you have an increased risk, go to, Dyshidrotic eczema: Causes.
Images used with permission of DermNet NZ: 2,3,4,6,7, 8
ReferencesAmini S, Burdick AE, et al. James WD. Dyshidrotic eczema . Medscape. Last updated 4/22/2020. Last accessed 9/30/2020.
Geria AN, Alexis AF. Atopic dermatitis and other eczemas. In: Taylor and Kellys Dermatology for Skin of Color. . McGraw Hill, USA, 2016:171.
McGovern TW. Dermatitis . In: Fitzpatrick JE, et al. Dermatology Secrets. Hanley & Belfus, Inc., USA, 1996:47-48.
Petering H, Christine Breuer C, et al. Comparison of localized high-dose UVA1 irradiation versus topical cream psoralen-UVA for treatment of chronic vesicular dyshidrotic eczema. J Am Acad Dermatol 2003 50:68-72.
Reider N, Fritsch PO. Other eczematous eruptions. In: Bolognia JL, et al. Dermatology. . Mosby Elsevier, China, 2018: 237-8.